How To Read A Report
This article explains the symbols and colour coding used on our reports. Most reports include a page titled 'How to Read the Report', which includes this same information.
Genes: Results are listed in order of the gene short name, for example GPX1.
SNP identifier: The 'rs' number is the reference sequence number that identifies a specific location on the genome. It is also known as a SNP (Single Nucleotide Polymorphism) pronounced 'snip', polymorphism or mutation. For example, rs1050450.
Personalised Result: Your genotype result is shown as two letters (A,G,T or C) which represent the DNA bases present at that location. Multiple attempts are made to achieve the required level of statistical confidence, but if that cannot be met it is reported as 'No result'.
Arrow Direction: The direction of the arrow indicates the potential effect of the SNP on gene expression, where applicable - it can increase or decrease activity, or neither. An 'up arrow' : up-regulates or increases the activity and effect on the gene. A 'down arrow': down-regulates or decreases the activity and effect on the gene. No arrow - no effect on the activity of the gene.
Highlight Colour: The genotype result highlight indicates the potential effect of the SNP on gene function in a particular context.
RED: the effect of the variant is negative
AMBER: the effect of the variant is somewhat negative
GREEN: no variation, or the effect of the variant is positive
The Pathway Diagrams use the following colour coding:
Blue - substrate (starting compound) or metabolite (resulting compound)
Purple - cofactor - vitamin, mineral or other food component which supports/ speeds up/ upregulates a gene or or gene product
Orange - inhibitor - vitamin, mineral or other food component which inhibits/ slows down/ downregulates a gene or gene product
