Alzheimer's Disease

The three subtypes of Alzheimer's Disease⠀

Dr. Bredesen (“The End of Alzheimer’s”) explains that there are three major subtypes or categories in Alzheimer’s, and identifying the one that the patient is dealing with can help implement a personalised program.⠀⠀

The first one is the inflammatory (hot) subtype. It is characterized by an up-regulated immune system which can increase inflammation and the risk of cardiovascular disease, insulin resistance, arthritis and the 'hot' sub-type of Alzheimer's disease.⠀

The second one is the atrophic (cold) subtype. It is associated with reduced support from hormones - thyroid (T3), adrenal (cortisol), sex hormones (oestrogen, progesterone, testosterone) - and Vitamin D, and is often accompanied by increased homocysteine and insulin resistance.⠀

The third one is the toxic (vile) subtype. It is characterised by hypothalamic-pituitary- adrenal axis (HPA) dysfunction, metal toxicity (mercury, lead or iron), high homocysteine and low zinc (and elevated copper) and/ or chronic inflammatory response syndrome (CIRS) - a reaction to mycotoxins (found in mould).

Alzheimer's Disease and Lifecode Gx reports

Genetic variances can be helpful in considering the different sub-types, as they are based on several genes. Our tests can identify your genetic predispositions and empower you to control through personalised diet and lifestyle actions. Our APOE Report analyses genes that can influence the development of Alzheimer’s including APOE, TNF and IFNG.

It examines the key genes and variants (SNPs) that can contribute to chronic health conditions such as Alzheimer’s disease and also cardiovascular diseases. It's however very important to always remember that genes are not your destiny and you can manage your risk by positive nutritional and lifestyle interventions.

For more information, please see our Free webinar recording on APOE genes here.